"Real Time" host Bill Maher had some tough words for Democrats who are circling the wagons around President Biden following his disastrous debate performance. 

"I have said before, I will vote for his head in a jar of blue liquid. After last night, time to get the jar," Maher quipped during the panel discussion Friday night. 

After reiterating his months-long call to replace Biden on the Democratic ticket, he stressed it is now "absolutely apparent" and that it is the "only way" for Democrats to win the election. 

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"The flash poll after, Trump, they said, won 67 to 33," Maher said. "33, that number rings in my mind. Because you know what that number is? That's the number you always see very close- 33, 34, 32 of the people who are just always with their party. I mean, this is Mrs. Goebbels in the bunker number… You see it on the right. They used to call them birthers, Tea Party, whatever MAGA nation, they never move. And now I feel like that's a third of the Democrats who are, like, they're gonna stick with this guy and they are going to regret it."

"He is going to lose. I said it nine months ago. I'm gonna say it again tonight. And now, it seems like it's so apparent," Maher continued.

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The liberal comedian then played the infamous clip from the debate where Biden said that his administration "finally beat Medicare." 

"It reminded me of when Mike Tyson used to knock guys out in 90 seconds. Like that was like two minutes into the debate and I went like ‘Oh, this election is over.’ That was like a haymaker," Maher said. 

"I feel like the whole rationale for Biden running has always been 'I'm the only guy who can beat him.' Now I think it's inverted. I think he's the only guy who could lose to him," he continued. "I keep hearing all day from these Democrats defending this. Like, 'we can't abandon Joe Biden.' What about me? I feel abandoned. I feel abandoned. I have nobody to vote for." 

Top Democrats including former President Obama have expressed support for Biden following his questionable performance at Thursday's CNN Presidential Debate.

"Bad debate nights happen. Trust me, I know," Obama said in a statement Friday. "But this election is still a choice between someone who has fought for ordinary folks his entire life and someone who only cares about himself. Between someone who tells the truth; who knows right from wrong and will give it to the American people straight — and someone who lies through his teeth for his own benefit. Last night didn’t change that, and it’s why so much is at stake in November."

Meanwhile, calls for Biden to withdraw from the presidential race have dramatically grown in the liberal media, most starkly from The New York Times editorial board. 

"Mr. Biden has been an admirable president. Under his leadership, the nation has prospered and begun to address a range of long-term challenges, and the wounds ripped open by Mr. Trump have begun to heal. But the greatest public service Mr. Biden can now perform is to announce that he will not continue to run for re-election," the Times editorial board wrote Friday.

Loofahs, also known as luffas, are a popular choice for cleansing and exfoliating the skin during bathing. 

Dermatologists, however, often advise against their use and suggest alternative tools. 

The primary concerns relate to hygiene and the risk of skin infections due to bacterial growth on the loofahs.

Loofahs, traditionally sourced from the fibrous interior of the luffa plant fruit, are used as a natural scrubbing sponge for cleansing and exfoliating the skin. This plant, part of the gourd family Cucurbitaceae that includes pumpkins and cucumbers, is peeled and dried to create the loofah sponge. 

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Known for their exfoliating properties along with the ability to lather and cleanse, loofahs have been a long-standing bathroom staple. 

Synthetic versions made from plastic or alternative materials are now commonly used.

Typically, loofahs are kept in the shower after use. The damp environment is a breeding ground for bacteria that clings to the loofah. 

Loofahs can be dangerous because they are a "microbe reservoir," according to MedicineNet.com. Since bathers use the loofah to scrub dead skin, the cells get wedged into the pores of the sponge, leading to bacterial growth.

The common types of bacteria that can grow on the loofah are Pseudomonas species and Enterobacteriales, says the National Library of Medicine. 

They can also become the habitat of other bacteria such as E. coli.

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Contaminated loofahs have even been linked to cases of Pseudomonas folliculitis, a skin infection caused by bacterium Pseudomonas aeruginosa that is usually developed from a public hot tub, pool or spa.

The bacteria that can thrive within the sponge, along with its potential to cause microtrauma due to abrasiveness, render loofahs an undesirable choice for many dermatologists. 

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They often suggest that if loofahs are used, they should be limited to once or twice a week and avoided entirely for several days post-shaving to prevent bacteria from entering through any small cuts on the skin.

It is generally recommended that you throw out a natural loofah after three to four weeks of use, which is also the recommendation of the Cleveland Clinic. 

Plastic loofahs can last for two months. If the loofah shows signs of mildew or mold, however, it should be discarded immediately. 

If you're convinced that you should remove loofahs from your bathroom routine, it's helpful to know the available alternatives. 

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Washcloths are a safer option since they can be washed frequently, reducing bacteria accumulation.

Silicone bath scrubbers are another alternative, although they require regular cleaning. 

Sea sponges are a natural choice that come with enzymes to deter bacteria. They lack preservatives and dyes. 

For those who prefer to continue using a loofah, it's essential to clean it thoroughly and ensure it dries completely after each use.