Duke sent the College Football Playoff picture into uncertainty with a stunning overtime win on Saturday.

The Blue Devils won their first outright ACC championship since 1962 with a 27-20 victory over Virginia.

Duke quarterback Darian Mensah connected with tight end Jeremiah Hasley for a 1-yard touchdown on a fourth-down play in overtime, in what would be the deciding score.

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Virginia quarterback Chandler Morris was intercepted by Duke's Luke Mergott on the Cavaliers’ first offensive play of overtime.

Duke last won a share of the ACC regular-season title in 1989, sharing it with Virginia in Steve Spurrier’s final season as the Blue Devils’ coach. The conference championship game was created in 2005, and Duke got there this year thanks to a five-team tiebreaker.

NOTRE DAME'S MARCUS FREEMAN MAKES CASE FOR COLLEGE FOOTBALL PLAYOFF 

Virginia, the ACC regular-season champion, would have reached the CFP for the first time in school history with a victory. While Duke is still unlikely to make the playoff field, the win opens the door for a second Group of Five team — likely James Madison — to sneak in.

JMU alums Ben Overby and James Turner were even at the game to support Duke.

"Nothing against UVA," Turner said excitedly, "but we’re just here to support Duke."

ACC commissioner Jim Phillips argued this week that his league deserved two bids: one for No. 12 Miami as the league’s highest-ranked team, the other for the Duke-Virginia winner as the league’s champion.

The Associated Press contributed to this report.

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Ohio State kicker Jayden Fielding missed a 27-yard field goal in the final minutes, as Indiana hung on to win the Big 10 football championship 13-10 on Saturday. For Indiana, it is their first outright conference championship since 1945, after winning a share of the title in 1967. 

The Hoosiers were four-point underdogs going into the game against the defending national champions, with the top seed in the college football playoff on the line. Now, before the playoff even starts, Indiana has clinched, arguably, its most successful season in the modern era. 

"I want to give all the glory to God. We were never supposed to be in this position, but by the glory of God, the great coaches, the great teammates, everybody around us, we were able to pull this off," Indiana quarterback Fernandeo Mendoza told Fox Sports after the game. 

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Mendoza passed for 222 yards with one touchdown and one interception to help pull off the win.

Indiana wide receiver Charlie Becker, who caught six passes for 126 yards, also said, "all glory to God," to Fox Sports after the win. 

NOTRE DAME'S MARCUS FREEMAN MAKES CASE FOR COLLEGE FOOTBALL PLAYOFF 

"The Hoosiers are real, and we're here," Becker said.

Indiana, now 13-0, will now look to win its first national championship ever in the college football playoff, as their statement win over Ohio State should all-but ensure the No. 1 seed when the tournament begins. 

Meanwhile, Ohio State is still likely to get a first-round bye despite the loss. 

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