Trump Announces U.S. Drug Pricing Deal With AstraZeneca

President Donald Trump unveiled a deal with U.K.-based drugmaker AstraZeneca on Friday under which the company will sell some medicines at a discount to the government’s Medicaid health plan in exchange for tariff relief, similar to a drug pricing pact reached last week with Pfizer.

The deals set a framework the White House will use to try to reach its goal of lowering U.S. prescription medicine prices. The president sent letters to 17 leading drugmakers in July telling them to slash prices. Pfizer and Astra are the first two companies to reach a deal with the administration.

AstraZeneca will also offer some of its drugs at up to 80% off their list price through the TrumpRx website planned for next year, CEO Pascal Soriot said at an event in the Oval Office.

He said the company will receive a three-year tariff exemption “to localize the remainder of our products.”

U.S. patients currently pay by far the most for prescription medicines, often nearly three times more than in other developed nations, and Trump has been pressuring drugmakers to lower their prices to what patients pay elsewhere or face stiff tariffs.

Last month, Trump threatened 100% tariffs, ratcheting up pressure on the pharmaceutical industry to agree to price cuts and shift manufacturing to the U.S., after negotiations broke down earlier this year, lobbyists and executives told Reuters following the Pfizer deal.

More than 70 million people are covered by Medicaid, the state and federal government program for low-income people. Drug spending in that program is dwarfed by that of Medicare, which covers people aged 65 and older or those with disabilities and is not included in Friday’s announcement.

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Medicare’s drug spending reached $216 billion in 2021, while Medicaid’s gross spending was around $80 billion.

The Medicaid program already receives the lowest drug prices in the U.S., so the additional savings may be modest, said Craig Garthwaite, a professor at Northwestern University’s Kellogg School of Management.

“If you look at AstraZeneca’s portfolio, I don’t think there are a bunch of drugs that exist where that’s going to involve them giving a very big discount to Medicaid,” Garthwaite said.

AstraZeneca’s Pfizer‑like deal may spare it tariffs, but will not move the needle on U.S. rising health insurance premiums and out‑of‑pocket drug costs, said Rena Conti, an associate professor at Boston University.

“It’s good for the companies, and has very uncertain if any benefit for Americans struggling with the affordability of prescription drugs,” Conti said.

Soriot has worked to keep his company close to Washington while pursuing its growth strategy.

AstraZeneca in July announced it will invest $50 billion in U.S. manufacturing and research and development by 2030. It will build its biggest site worldwide in Virginia, and expand facilities in five other U.S. states.

In September, the company announced it will sell its diabetes and asthma drugs direct to cash-paying U.S. patients at a discount of up to 70% off list prices, another move in response to Trump’s pressure campaign.

Soriot this year has played up the company’s U.S. credentials. He described the Anglo-Swedish firm as a “very American company,” highlighting its identity shift toward its largest market. AstraZeneca will list its shares in the United States as well as its current markets in the UK and Europe.

(Reporting by Steve Holland in Washington and Michael Erman in New Jersey; Additional reporting by Jarrett Renshaw and Ahmed Aboulenein in Washington, Maggie Fick in London, Patrick Wingrove in New York and Mariam E Sunny in Bengaluru; Editing by Caroline Humer and Bill Berkrot)

Layoffs Hit IRS Amid Shutdown Standoff, And They’re Bigger Than Anyone Thought

Fourteen-hundred employees at the Internal Revenue Service will be laid off in a process initiated Friday, The Daily Wire has learned.

The number is larger than anyone expected, with the IRS union filing a lawsuit to stop what it said it had “heard” might be 1,300 layoffs across the entire Treasury Department. The real number, an Office of Management and Budget official told The Daily Wire, is 1,400 at the IRS alone, plus more at other components of Treasury.

The layoffs come as Democrats refuse to fund the government at all unless the Republican majority agrees to increased spending for non-citizens’ health care and other topics. That has resulted in a government shutdown, wherein employees are sent home and traditionally receive back pay one a deal is reached.

The Trump administration has countered that if federal employees are going to be prohibited from working due to a shutdown, some will never come back at all – particularly those that staff agencies favored by Democrats.

The IRS was targeted as a bloated agency that Democrats have used for political purposes, including targeting conservative nonprofits, the OMB official said. The official said the tax collecting agency spent $35 million on guns, ammunition, and military-style weaponry between 2006 and 2023, and advertised job postings that said special agents must be willing to use “deadly force.”

The official said unnecessary and redundant employees would be targeted, with those focused on the prompt processing of tax returns protected. Still, cuts to the revenue-collection agency mean that Democrats’ efforts to increase government spending in the short term could backfire, with the ability to collect increased revenue diminished.

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Politico reported that layoffs are likely to also affect the departments of Interior, Homeland Security, Commerce, Education, Energy, Housing and Urban Development, and Health and Human Services, as well as the Environmental Protection Agency.

The government has been shut down for ten days, and the Senate failed to reach a deal Thursday night.

The Daily Wire reported Friday that Senate Majority Leader John Thune (R-SD) said Republicans held off on layoffs for 10 days to give Senate Democrats a chance to agree to agree to extend government funding at existing levels, but that now, “this gets real.”

Senate Minority Leader Chuck Schumer countered, “Nobody’s forcing Trump and [OMB Director Russ Vought] to do this.”

Related: ‘The Government Can Destroy Anyone’: How An IRS-Led Global Alliance Ruined An Innocent American Banker

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